Dermatan sulphate proteoglycans
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Dermatan sulphate proteoglycans chemistry, biology, chemical pathology

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Published by Portland Press in London, Chapel Hill, NC, USA .
Written in English


  • Dermatan sulphate.,
  • Proteoglycans.,
  • Glycosaminoglycans.,
  • Extracellular matrix proteins.

Book details:

Edition Notes

Statementedited by John E. Scott.
ContributionsScott, John E., Harden Discussion (8th)
The Physical Object
Paginationxv, 374 p. :
Number of Pages374
ID Numbers
Open LibraryOL18074220M
ISBN 101855780518
LC Control Number93065748

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Additional Physical Format: Online version: Dermatan sulphate proteoglycans. London ; Chapel Hill, NC, USA: Portland Press, © (OCoLC)   Dermatan sulphate proteoglycans were purified from juvenile human articular cartilage, with a yield of about 2 mg/g wet wt. of cartilage. Both dermatan sulphate proteoglycan I (DS-PGI) and dermatan sulphate proteoglycan II (DS-PGII) were identified and the former was present in Cited by: Dermatan and dermatan sulfate proteoglycans have also been implicated in cardiovascular disease, tumorigenesis, infection, wound repair, and fibrosis. Growing evidence suggests that this glycosaminoglycan, like the better studied heparin and heparan sulfate, is an important cofactor in a variety of cell by:   Proteoglycans bind multiple components of the extracellular matrix by serving as important regulators of cell behavior. Given the influence of culture architecture on cell function, we investigated whether switching NIH3T3 fibroblasts from growth on type 1 collagen in monolayer to a collagen gel might influence dermatan sulfate expression.

Dermatan sulphate proteoglycans edited by J. E. Scott, Portland Press, £ ( pages) ISBN 1 Cited by: Heparan sulphate and chondroitin/dermatan sulphate proteoglycans of human skin fibroblasts were isolated and separated after metabolic labelling for 48 h with 35SO4(2-) and/or [3H]leucine. Available evidence shows that there are two species of small dermatan sulphate and keratan sulphate proteoglycans. It is suggested that each species is specific for its own band (a, c, d or e).   White Matter Extracellular Matrix Chondroitin Sulfate/Dermatan Sulfate Proteoglycans in Multiple Sclerosis Raymond A. Sobel, MD Department of Pathology (RAS), Stanford University School of Medicine, Stanford, California and Veterans Affairs Health Care System, Palo Alto, California; Loyola University, Stritch School of Medicine (ASA), Maywood Cited by:

  Coster, L., Hernnas, J., and Malmstrom, A. () Biosynthesis of dermatan sulphate proteoglycans. The effect of beta-D-xyloside addition on the polymer-modification process in fibroblast cultures. Biochem. J. (Pt 2), – PubMed Google ScholarCited by:   Endocan was secreted as a dermatan sulfate proteoglycan by endothelial cells. Because DS is known to affect both the generation of thrombin in vitro (46) and coagulation, the potential anticoagulant activity of endocan was tested on APTT, TCT, . The properties and turnover of hyaluronan / Torvard C. Laurent, J. Robert E. Fraser --Cartilage proteoglycans / Timothy E. Hardingham, Matthew Beardmore-Gray, David G. Dunham, Anthony Ratcliffe --Biological roles of dermatan sulphate proteoglycans / L.C. Rosenberg, H.U. Choi, A.R. Poole, K. Lewandowska, L.A. Culp --Common structures of the core. It was shown that loss of sulfated proteoglycans and anionic regions in the basal membrane of the glomerulus and the mesangial mat rix caused excess accumulation of proteoglycans such as chondroitin sulphate and dermatan sulphate in these areas.3 This causes a decrease in charge-dependent renal selectivity and an increase in the thickness of the basal membrane.